Treating GERD with PPIs
How Stomach Acid Is Produced
Acid is produced by cells in the stomach lining called parietal cells. Inside these cells, the actual production of acid is done by little chemical pumps known as proton pumps. These proton pumps have two states – active (producing acid) and inactive (not producing acid). The pumps are activated when special sensors in the stomach detect that the pH of the stomach fluids have risen to a higher level (less acidic). The main way that this happens is when you eat a meal. They can also be activated by other means, which I will mention later.