Home › Forums › Infant Reflux Support › HELP!!! › PPIs and H2s
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February 27, 2006 at 11:26 pm #2634
Anonymous
InactiveOk I know some of you have your babies on both PPI’s and H2 blockers, my dr says NO WAY can’t be done. So, I was wondering if any of you have a website or an article you can send me so I can prove her wrong. Jack is no longer eating and she has been dragging her feet for almost 3 months now and I need to help my son ASAP because obviously his dr. won’t.
Thanks,
Cris
February 28, 2006 at 10:18 am #2651Anonymous
Inactiveyou can go to marci-kids and get some literature. I know that Joel is a big advocate for reflux babies and very knowledgeable on the meds. Try to email him, maybe he could forward you something.
Also, my docs. were the ones that prescribed zantac and prevacid for my baby only after i asked them too. They didn’t know anything about seperating the 2 drugs by 2 hours so they didn’t cancel each other out. I still use zantac at night for my dd even though she is on prevacid. It helps control the acid, and she tends to sleep longer without wake ups.
February 28, 2006 at 12:02 pm #2660Anonymous
InactiveMy pedi gi said she would rather us add in zantac than up prevacid past 15mgs. Regular pedi also wrote a script for zantac in combo with the prevacid. I know that isn’t overly helpful as you need data not personal experience. I would ask your doc to prove to why it can’t as opposed to you proving why it can. Some docs really just don’t know. It is impossible for them to know about everything, this might be one area where your doc is behind the times
February 28, 2006 at 3:12 pm #2677Anonymous
InactiveMy son is 31 months old (35lbs) and is on 15 mg of Prevacid in the morning and 10mg of Pepcid AC chewable tablets in the evening. He started on 15 mg of prevacid, then around the age of 2 – I began to hear him refluxing again, so I upped the dose to 30 mg of prevacid (15 mgs twice a day). That didn’t help, then I read about the PPI AM/ H2 Blocker PM option. He’s been on that “combo” for over a month now and I am a true believer!!! He is finally sleeping through the night, he’s happier during the day, and I don’t hear him refluxing anymore. I should also mention that my son started out with zantac alone at 2 weeks old and it didn’t do a thing for him. I think the combo is the way to go!
http://www.peds.ufl.edu/prp/prp_fellows/gastro/gerd-ee-hp.pdf
The above link is from a Power Point Presentation done by the Pediatric GI Dept at the University of Florida in May 2005 on page 16 it says that PPIs work the best, but in severe cases you may add a H2 blocker in the evening. Also, NOTE that there are recommendations for the amount of PPI per KG that they should have. (devide pounds by 2.2 to get Kilograms) and that PPIs should be split into 2 doses a day (unless you’re doing the H2 blocker in the PM) because their metabolisms are so high.Here is the article that I showed my son’s GI doc: http://www.aboutkidsgi.org/GERD.html the paragraph that starts with “Proton Pump…” the LAST sentence of that paragraph says that a “Concomitant administration of a h2-receptor antagonist in the evening appears effective in such individuals” Hope that helps!
lansima2006-2-28 15:20:12
February 28, 2006 at 3:13 pm #2678Anonymous
InactiveIt is true that H2 blockers like Zantac and Pepcid should not be given at the same time as a PPI like Prevacid or Zegerid, as the H2 blocker will interfere with the PPI and make it less effective. But according to Dr Phillips, they can be given if they are spaced out at least 4 hours apart from one another. I do not have any studies to point you to unfortunately, just Dr Phillips’ word. He also often says that if a child is on the right dosage of PPI, an H2 blocker should not be needed, and that it’s always best to give an optimal dose of one drug rather than give a suboptimal dose of two drugs.
February 28, 2006 at 10:20 pm #2722Anonymous
InactiveThanks my doc’s response was “it’s not FDA approved”
So she put him on 7.5mg of prevacis caps a day, is this enough?
Cris
March 1, 2006 at 11:47 am #2752Anonymous
InactiveCris,
While I can’t answer your original question (I’m new to this whole reflux thing) I will suggest finding a different doctor. Our initial pediatrician claimed he “couldn’t” write a script for a PPI for an infant because he insurance companies “wouldn’t let him”. What a bunch if B.S! He simply didn’t want to because he didn’t believe our DD had silent reflux. He kept saying “Some babies are just fussy”.
We switched docs, the new one immediately agreed that she has reflux and while we’re working with Zantac now he did say we would try a PPI next. Get a new doc who is more responsive.Karen
March 1, 2006 at 12:34 pm #2758Anonymous
InactiveWhat is Jack’s current age and weight? That is a very low dose of Prevacid, and it will most likely not have any effect. Most doctors are not aware of the fact that infants metabolize and eliminate PPIs at a rate 3 times faster than adults and so they need to be given higher doses with greater frequency throughout the day.
March 1, 2006 at 12:53 pm #2761Anonymous
InactiveTake him to a GI doc (I assume the doctor you’re referring to is your son’s pediatrician). I hate to say it, but I sometime think that pediatricians only know how to treat ear infections and that’s all they’re comfortable diagnosing. I know several moms that talk to their childs surgeon/ent doc/GI Doc/or Pulmonologist when they are looking for answers and forget the pediatrician.
March 1, 2006 at 4:05 pm #2780Anonymous
InactiveJack is 6.8 kilograms
I’m trying to leave the island next week and his ped is trying toget him into Walter Reed, it’s just taking forever and I’m not really looking forward to making the 21hour journey w/ a 5 month old.
Cris
March 1, 2006 at 4:24 pm #2783Anonymous
InactiveAt that age/weight, Dr Phillips would recommend that your son be given 30 mg of Prevacid per day, split into 2 or 3 doses (preferably 3, but I know it’s hard to split up that kind into more than 2 doses). I think you would see a marked improvement at this dose. PPIs are also a very safe drug, working only at the site of acid production, and you do not need to worry about overdose or side effects.
March 1, 2006 at 7:06 pm #2791Anonymous
InactiveTHANK YOU!!!
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