Infantreflux.org | PPIs, H2 blockers, and antacids

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October 31, 2006 at 2:17 pm #16932

Anonymous
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I just bumped a thread that includes a discussion about this, but I thought that I would copy Joel’s comments about this from a previous post. A lot of people- including myself- have been wondering how to space these meds properly. Note that when talking about spacing the mylanta and the PPI, he differentiates between immediate and delayed release. (Laura, maybe could you link this to your intro?)

RefluxSol
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Posted: 21 June 2006 at 11:08am | IP Logged

Lori,

It is PPIs and H2 blockers like Zantac, Axid, Tagamet, or Pepcid that you should not give within 4 hours of a PPI dose. If you are using an enteric coated form of PPI, then you should not give an antacid within about an hour of the PPI dose because it can destroy the coating and expose the drug to pockets of acid in the stomach. But with CaraCream or Zegerid it is fine to give it along with an antacid.

s&h’s mum2006-10-31 14:18:55

October 31, 2006 at 2:22 pm #16933

Anonymous
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Thanks Lori!

October 31, 2006 at 3:35 pm #16942

Anonymous
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bump!

October 31, 2006 at 4:26 pm #16947

hellbennt
Keymaster

so mylanta can be given with a PPI?

It can be given w/ zantac/tagament/axid/pepsid…(right?)

October 31, 2006 at 9:45 pm #16962

Anonymous
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I don’t know about giving mylanta with an H2 blocker. He doesn’t talk about that. But as far as mylanta and PPIs and PPIs and H2 blockers it seems that:

1. PPIs and H2 blockers should not be given within 4hrs of each other.

2. Mylanta (or any other antacid) should not be given within an hour of any delayed release PPI (such as prevacid capsules/solutabs, and prilosec capsules/tablets/MUPS).

3. Mylanta (antacid) can be given any time relative to an immediate release PPI (Zegerid/CaraCream, or a properly compounded suspension).

January 20, 2007 at 4:20 pm #22770

Anonymous
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bump

March 26, 2007 at 2:00 pm #28529

Anonymous
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bump

July 1, 2007 at 5:49 pm #38365

Anonymous
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I am new to all this. How do you know if it’s immediate or delayed release? We’re on the compound prilosec. I’d assume that’s immediate, but I don’t really know. Thanks

July 1, 2007 at 5:50 pm #38366

Anonymous
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Sorry – all the messages didn’t show up when I first opened this. Now I see the answer to my question.

October 2, 2007 at 5:40 pm #43656

Anonymous
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bump

September 23, 2008 at 10:03 pm #57044

Anonymous
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Question…… what are the effects of giving an infant Mylanta? We were on Zantac and it helped at first then upped the dosage a few times and then just kinda stopped. she’s been off her zantac for just about a month, but recently the past week has been showing signs again of her reflux… refusing to eat, only eating a little, absolutely miserable, arching the back, hiccups, wet burps, (she had silent reflux), so we have been giving her mylanta the past few days and it has been working great for her… but what are the long term effects on this? we have a pedi appt tomorrow morning, hes going to freak knowing i gave her mylanta without talking to him. but he just doesnt care about her well being, he told me it was colic and wouldnt believe me it was reflux. so that leads to another question…. can a pedi prescribe a PPI or do you have to see a specialist? kimRy042008-09-23 22:04:18

September 24, 2008 at 8:01 am #57050

hellbennt
Keymaster

so glad to see your post!

(this is an old thread, so you might want to move further discussion to a new topic)

mylanta cherry supreme is perfectly safe for babies; there’s no aluminum. the ‘only’ side effect you may see is loose stools. if that happens then back of a bit.

mylanta cannot be given at the same time as a PPI. it CAN be given at the same time as zantac.

zantac is very weight sensitive. here is the dosing for it (it is often underdosed- I inquired about this- read here):

Zantac dosing- my/other’s question (has axid dose too): https://www.infantreflux.org/forum/forum_posts.asp?TID=9539&PID=82914#82914

many, if not most, find babies plateau on zantac & then they ‘move’ on to a PPI. again, PPIs are oftentimes under dosed. http://www.marci-kids.com

is at the forefront of PPI dosing in infants research.

it can take a full 14 days to see the effects of the PPI, so when switching it is important to stay on the zantac (given 4 hrs seperate from the PPI), bcse otherwise it’s as if baby isn’t on any meds at all.

any dr can prescribe a PPI. many have found success w/ family drs, if they have not w/ their ped or ped GI.

have you read groupie intro?

Groupie Intro: my intro: https://www.infantreflux.org/forum/forum_posts.asp?TID=853&PN=1&TPN=1

‘see you’ on another page

September 24, 2009 at 7:33 pm #64047

Anonymous
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i know this is an old post, but I’m confused after visiting our Pedi.
She prescribed my 5 month old daughter both prevacid and zantac, and told me that I do NOT need to space them out. She said take them together. Is she wrong?

September 25, 2009 at 7:36 am #64051

Anonymous
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Yes, she’s wrong. You can take them both, but they need to be spaced apart. The other thing that marci-kids always said, is that if you get the dose of the PPI right, then in theory, you shouldn’t need the zantac. What’s your daughter’s dose again?

September 25, 2009 at 12:26 pm #64059

Anonymous
Inactive

hi Lori,
her dose right now is 15mg 2x a day, with 1.4ml zantac 3x a day. I’m not sure how I’m going to plan this.
I’m starting to lose faith in our doctors. Zegerid didn’t do anything for our DD, so now her ped wants her to go back to Prevacid and added zantac. I told her prevacid stopped working, that’s why we tried zegerid. BUt she said if it combines with zantac it will work better:(
Also, she told me yesterday that most of her patients do not do well on prevacid only, but they respond to prevacid AND zantac. She also told me that there was a study that came out this spring that studied the effective of PPI’s on infant, and the conclusion is PPI’s don’t work on them. I will do more research on this.
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