We went through periods like that with Hailey. Actually, it was usually teething, or a virus, or something else that caused her to suddenly start vomitting.
The other possibility is that his acid isn’t being well controlled despite the dose increase. I know that PPIs don’t stop vomitting, but when the acid is controlled it actually stops irritation of the esophagus and the LES, which creates a cycle. We’ve been told that when the acid isn’t well controlled, it can irritate the throat and LES causing more vomitting then you would otherwise see. We definitely saw this with Hailey- if she missed a few doses she went from a silent refluxer to a heavy puker.
Also, I don’t want to sound pushy, because I’m glad that your compound has worked well for your son to this point. But we had a lot of problems with compounds, so I’m always skeptical. Marci-kids says that for a compound to be effective, it needs to be made with at least 16.8 percent sodium bicarb (for any doses under 7ml) and that each dose needs to have at least 3.5ml to ensure enough buffer per dose. They should be made somewhere between 2-4mg/ml and with no added flavourings whatsoever, including simple syrup, stevia powder and other sweeteners.
Good luck.
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