Solutab spit-up two hours after dose

[Anonymous]

Is this strange? I gave my baby her 30 MG solutab at 6:30am, followed by bottle at 7am. At 9am I put her down for tummy time and she spit up a little bit. At first, I thought there was blood in the spit up, but on closer look, it was a bunch of the little pink prevacid granules! How could they sit in her tummy for 2 & 1/2 hours?? I don’t think she has motility issues because she was in the NICU for 3 months and believe me, they check for that, and she always had an empty tummy before the next feeding (3 hours apart). I left a message for her doctor, but wondered if anyone else ever had this happen. She’s been on the solutabs for about 3 weeks. It just seems weird that the milk had all digested and the solutabs were still in her tummy (the spit up was mostly clear with the pink granules, not much milk). (Sorry to be so graphic!)

Thanks

Marys Mom

6-28-05 @ 27 weeks

[Anonymous]

i’ve seen my daughter spit up purple (prevacid) 6 hours after she had her meds. i think that sometimes it is just a fluke.

[Anonymous]

Thanks for replying. Yes, the prevacid was dark pink, almost purple. I have to think it was a fluke as I have never seen her do this before.

[Anonymous]

Just wanted to report, dr’s office called back and said sometimes what happens is the medicine gets absorbed and digested, but the cellulose stays in the tummy for a little while, which explains the purple granules coming back up. Said not to worry about it unless she’s doing this often (not a rare occurrence).

Just FYI!

[Anonymous]

After doing some research on this site on purple vomit (what has my life come to?), I found this quote from Joel on another post:

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Well, I wouldn’t say that it’s really “normal”. The fact that it is purple means that the Prevacid has been degraded by the stomach acid and is no longer effective. PPIs turn purple or pinkish brown when they are degraded by acid. The form of Prevacid that you are talking about is made up of enteric coated granules. The enteric coating is supposed to protect the drug from the acid long enough for it to be passed out of the stomach, and into the less acidic duodenum, where it is then absorbed into the blood stream. But if you see purplish flecks in the spitup, that means that some (if not most) of the medicine is not making it to the duodenum before it is degraded by the acid.
That is one of the main reasons why we do not recommend enteric-coated forms of PPIs, and why instead we recommend immediate-release Zegerid, which is absorbed into the blood stream directly from the stomach.
—-

My question is, maybe I’m not administering it properly? I do give the solutab with some water (maybe 20ccs) on an empty stomach, and then wait a half hour to feed. My pharmacist said it is better to wait 1 hour, but I question whether my baby can wait that long. Then again, since this has never happened before, maybe I’ll just continue “as is”.

[Anonymous]

No, I think you’re administering it correctly and I agree that you would probably have a hard time getting her to wait a whole hour before her meal. As I said in the post you quoted, this is a big problem with giving enteric-coated forms of PPIs to infants. The drug can only be absorbed in the small intestine, but it often sits in the stomach so long that the protective coating is broken down and the drug is degraded by the acid before it can work. I would try to get a presciption for either Zegerid or an unflavored compound of Prevacid.

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