Home › Forums › Infant Reflux Information › Medicines › Zantac Dosing (axid pepcid, too)
Tagged: axid, otc zantac, pepcid, zantac
- This topic has 20 replies, 1 voice, and was last updated 13 years, 9 months ago by
hellbennt.
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May 3, 2007 at 9:32 am #32116
hellbennt
KeymasterAdding this here, to keep everything in one place:
To make your own zantac liquid using otc zantac
(use your own judgement! Disclaimer! I cannot tell you to do this. Research & make your own educated decisions!)You can crush a 75mg Zantac (ranitidine) tablet. Put this in 10 mL of the Mylanta Cherry Supreme.
(Mylanta Cherry Supreme is the one variety of mylanta that does not contain aluminum.you can’t find it anymore, but you can find store brand equivalents. Try rite-aid, cvs brand, wal mart, target, Bartell Drug (West coast), Dollar General, brand names: Geri-Care & Geri-Lanta Supreme, meijer, etc- just look for one that does not list aluminum in the ingredients. you can give 1ml up to 5 times a day- it’s safe, even for newborns. if you see loose stools back off.)
Let the mixture sit for a few hours, shaking occasionally so that the pill dissolves entirely & shake before dosing. You do not have to keep it in the refrigerator. Give 2.5mL per dose, 2 times per day.
(use your own judgement! Disclaimer! I cannot tell you to do this. Research & make your own educated decisions!)POST#6 of this thread explains the zantac dosingPOST#7 of this thread has pepcid & axid dosingPOST#7 of this thread has more zantac info & also how to make your own liquid zantac, using otc zantacPAGE 3 of this thread has pound to kilo conversion chart~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~hey everyone,I’m putting this here, not the Medicines forum, because I don’t want to scare any newcomers…
anyway, I went to the peds office yesterday bcse Ari has an ear infection that won’t clear up (grr
& grr
to my ownself bcse I haven’t been doing as I say- w/ the saline- I’ve been slacking) & I was chatting w/ the ped about another mom who I’ve helped a bit w/ reflux and I showed off my knowledge by spouting off about zantac dose being 5-10mgs per kilo & she totally contridicted me, whipped out the Pediatrician’s Reference Guide or whatever that book is, and showed me that Zantac dosing is 2-4mgs/kilo.
She told me my info must be outdated & I countered well that maybe Ped GIs go by something else?- she didn’t respond to that…
SO: I don’t have the time right now to sit & google, but if anyone (hey where’s our resident pharmacist, LOL) wants to figure this thing out, please do (if anyone is contacting dr. philips for anything else could you aks about this too?). I feel really awful if I’ve been telling the wrong thing
…on the otherhand, I don’t ‘feel’ like 5-10mgs/kilo is wrong, that’s why I’m posting to you fabulous folks
BACK TO PREVACID 101, last post on the page (if you need to go back!)https://www.infantreflux.org/forum/forum_posts.asp?TID=1936&PN=0&TPN=1
Here’s a handy chart to convert lbs to kilos:hellbennt 2012-06-26 17:40:18 May 3, 2007 at 2:00 pm #32138Anonymous
InactiveLaura,
When we first suspected reflux in Brianna, I was actually on an extended visit to my family. I called my ped from back home and she told me Zantac was the first thing to try and that the dosage was 5-10mg/kg…unless they have changed the dosage within the past year…that is what she said…actually, my ped GI has always (as of sept was the last time he wrote me a script) said 5-10…hum….
May 3, 2007 at 3:17 pm #32145Anonymous
InactiveLaura,
I have a great article at work with the dosages considered recent from peer reviewed studies. But it’s not marci-kids data. It’s come from studies they’ve done on kids, they acknowledge higher dosing, but still not as high as marci-kids for PPIs, so I don’t know about H2 blockers. I’ll check it out anyhow. Dr. Phillips mentioned something called the Harriet Lane Handbook for dosing of medicine in children, but I’ve never heard of it.
I’ll let you know what I find.
May 4, 2007 at 2:12 am #32175Anonymous
Inactivehttp://www.cryingoverspiltmilk.co.nz/MedicalTreatment/Medica tionwithDosages.htm
This website gives dosages from NZ…they say 4-8mg per kilo (so similar to what you are saying).
May 4, 2007 at 2:17 am #32176Anonymous
InactiveThis pdf site is from one of the divisions of general practice in Aus…(family drs).
http://www.sdgp.com.au/client_images/18182.pdf
suggests mylanta at .5mg per kilo up t 5 x a day. Zantac at 5mg per kilo.
May 4, 2007 at 8:28 am #32178Anonymous
InactiveAs a pharmacist, I have a handy little electronic device called an ipharmacist which is updated regularly with all the current dosing. I have just checked it and this is what it says for oral pediatric dosing of zantac:
Duodenal and gastric ulcer: children 1 month to 16 years: 2-4 mg/kg/day divided twice daily to a maximum dose of 300 mg/day
GERD and erosive esophagitis: children 1 month to 16 years: 5-10 mg/kg/day divided twice daily. GERD max dosage: 300 mg/day. erosive esophagitis max dosage: 600 mg/day
May 4, 2007 at 8:36 am #32179hellbennt
KeymasterPOST # SEVEN (7) OF THIS THREADaHA!!! thank yoU sheri!!![And: here’s this link, which tells Drs where ELSE zantac dosing info is written, in addition to the ipharmacist!:
Here’s a handy chart to convert lbs to kilos:To make your own zantac liquid using otc zantac(use your own judgement! Disclaimer! I cannot tell you to do this. Research & make your own educated decisions!)You can crush a 75mg Zantac (ranitidine) tablet. Put this in 10 mL of the Mylanta Cherry Supreme.(Mylanta Cherry Supreme is the one variety of mylanta that does not contain aluminum.you can’t find it anymore, but you can find store brand equivalents. Try rite-aid, cvs brand, wal mart, target, Bartell Drug (West coast), Dollar General, brand names: Geri-Care & Geri-Lanta Supreme, meijer, etc- just look for one that does not list aluminum in the ingredients. you can give 1ml up to 5 times a day- it’s safe, even for newborns. if you see loose stools back off.)
Let the mixture sit for a few hours, shaking occasionally so that the pill dissolves entirely & shake before dosing. You do not have to keep it in the refrigerator. Give 2.5mL per dose, 2 times per day.~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~The following information is copied from the links provided (posted by Sheri, MFPIx2)AXID DOSE link:
Posted: 24 September 2007 at 11:19am Here is recommended dosing of Axid (also called nizatidine) for the treatment of GERD in infants and children:Children <12 years: 10mg/kg/day divided into two daily doses.However, Lexi-Drugs states that Axid may not be as effective in children under the age of 12 years as it is for adults and children 12 years and older.Children >12 years: 150 mg twice a dayPEPCID DOSE link:
Posted: 26 August 2007 at 11:17am Hi Yani,
I’m a pharmacist, and hopefully I can help a bit with Pepcid dosing recommendations for infants. First of all, what is the strength of the Pepcid suspension you were given? This is important to know because the dosing guidelines always refer to mg of drug, which you then use to figure out how many mL of suspension to give.
Here are the dosing recommendations (from my ipharmacist) for Pepcid in the treatment of GERD in infants and children:
Infants < 3 months: 0.5 mg / kg / dose given once dailyInfants 3 – 12 months: 0.5 mg / kg / dose given twice dailyChildren 1 – 12 years: 0.5 mg / kg / dose given twice daily (maximum of 80 mg / day)So for Daniel, being 2 months old and weighing approximately 5.25 kg, the recommended dose would be 2.625 mg given once daily. You could likely safely round this up to 3 mg per day since these types of medications (H2 blockers) are generally very safe and have very little if any side effects.I hope this helps some, but like I mentioned above, you need to know the strength of the suspension you have (in mg / mL) in order to figure out the appropriate dose.Good luck!hellbennt 2012-06-26 17:40:35 May 4, 2007 at 9:27 am #32183Anonymous
InactiveNo problem!
May 4, 2007 at 7:20 pm #32252Anonymous
InactiveDon’t you think pharmacists come in much more handy than Drs
May 5, 2007 at 5:00 pm #32302Anonymous
InactiveNot the ones in my area… neither one of them seem to know what they’re talking about most of the time.
s&h’s mum 2007-5-5 17:4:44 May 5, 2007 at 5:12 pm #32303Anonymous
InactiveActually, this thread raises a bit of a dillemma for me. If doctors and pharmacist use these guides to provide the right dosage of H2 blockers, then what happens when it comes to PPIs. I don’t know if that makes sense, but doctors need something that they consider the “gold standard” for how to treat reflux, and according to everything I’ve read, those are the standards set out by NASPGHAN (even in that great article that was posted), and they suggest much lower doses then marci-kids. As I said in another thread, I just got access to a great database at work called up-to-date, and it’s supposed to cite the “gold standards” for almost every medical and pharmaceutical treatment based on the current information and literature. It’s intented to be used at point of care so that doctors know what’s right. That brings me to the dillemma, which is that this database cited MUCH lower doses than marci-kids, even citing tons of studies used to dictate the dosing, including the ones on the marci-kids site. It even made a reference to something from one of Dr. Phillips’ studies in one of them. It makes me feel confused- if we get dosing for zantac from these guides, then what about PPI dosing. I don’t even know if you can follow this train of thought, I guess I’m just trying to figure out what the right thing is to do…. if my doctors have been following what’s supposed to be the “gold standards” research wise, maybe they’re not as off base or out of date as I’ve pegged them to be.
May 5, 2007 at 7:11 pm #32324Anonymous
InactiveLori, you have a great point.
To me the problem is that research can basically tell us anything we want to hear, two people can read the same research article and come to different conclusions, statistics can tell us anything……..so there is not “fact” in science.
Then some agency choses to come up with a “gold standard”. They do a literature review, throw out most of the research they find because they don’t reach the parameters that they set for inclusion and then base their “gold standard” on a few select research studies.
An example is brain injury, when doing literature searchs people often exlude the studies where people have a brain injury and a psychiatric problem co-existing. They then base their “facts” on only the studies with people who have a brain injury. They then suggest this or that type of med or technique does or doesn’t work. The problem is a large percentage of people with brain injury do have a psychiatric history as well….so how relevent are the results of the literature analysis and subsequent reccos.
It takes a long time for research to catch up with standards as well, I think. There are many examples of new treatments being underused until suddenly it “saves someone importants life” and all of a sudden it is in the news and people are going, well heck why can’t I get this…and then the government rush it through approval and it gets to become the “gold standard”.
I don’t know if you know much about Gardivsal the new cervical cancer vaccine, but it was designed in Aus and you guys approved it for use before us. It was only after you guys approved it that it came to the attention of the media….and guess what…it can save lives…so all of a sudden there was a community uproar….and hey presto the government rushed it through approval and it is now give for freeeee!
My very long winded point is that the “Gold Standard” is based on one particular point in time and one particular person or group of peoples reccos. So I think Drs are doing what they are trained to do by relying on “standards”, but perhaps some are not always thinking carefully and analytically about things and questioning things (like they are also trained to do).
Two different drs in two days gave me a differnt opinion on Alana’s health…there is only some science in medicine
Sorry, I’ll get down of my soap box now…sorry if I offended anyone
May 5, 2007 at 8:50 pm #32335Anonymous
InactiveThanks Therese. I love having someone else who will gab about research, so absolutely no offense taken (if you were directing that at me). I’ve decided to PM you to talk a bit more instead of continuing the discussion in the open forum since people might not want to hear more about this, and I definitely don’t want to cause needless drama on the site. But I would also like to talk about it some more. Hope that’s okay with you (and everyone).
May 6, 2007 at 4:59 am #32358Anonymous
InactiveLori, I answered your PM, but you are full
. Luckily I saved it somewhere else first so am ready to post it as soon as you are empty
.
May 6, 2007 at 9:09 am #32360Anonymous
InactiveThanks Therese! I’ll empty it now.
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